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They can positively impact enteric diseases and oxidative stress by altering gut microbiota composition and producing short-chain fatty acids (SCFAs) (214)

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Urinary excretion of biopyrrin was markedly increased in pediatric patients experiencing acute exacerbations of AD, with levels averaging 1.8 times higher than those observed in healthy individuals (65)

Depletion of cellular GSH, ranging between 61 and 88%, had a differential effect on the sensitivity to PtII vs PtIV drugs in the three cell lines: cytotoxicity of the PtIV drugs, tetraplatin and CHIP, was substantially enhanced in both the resistant and sensitive cell lines

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